BDBM50001493 3-Propyl-3,7-dihydro-purine-2,6-dione::3-Propyl-3,7-dihydro-purine-2,6-dione(enprofylline)::3-Propylxanthine (enprofylline)::CHEMBL279898::ENPROFYLLINE

SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O

InChI Key InChIKey=SIQPXVQCUCHWDI-UHFFFAOYSA-N

Data  38 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50001493   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi:  4.73E+3nMAssay Description:Antagonist activity at adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Institute

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity to rat adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi:  8.13E+4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2a receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAdenosine receptor A2a(GUINEA PIG)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataKi:  9.06E+4nMAssay Description:Affinity against adenosine A2 receptor in the brain membranes measured by the displacement of [3H]-CPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50001493(3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3...)
Affinity DataEC50:  7.20E+3nMAssay Description:Relexant activity on the spontaneous tone of isolated guinea pig tracheal ring chains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank